Kusuriya no Hitorigoto Movie is a spin-off of the original series, adapting the story of Hakuho Kikumura, a young apothecary who poses as a man in order to protect her family's pharmacy in 18th-century Kyoto. Hakuho's complex relationships with the people around her, particularly the high-ranking samurai Shigure Kosaka, play a significant role in the narrative. The movie delves into themes of identity, loyalty, and the consequences of deception in feudal Japan.