The series follows Rokudo Rokujin, a young boy with the ability to see and communicate with yokai, supernatural creatures from Japanese folklore. As a member of the Nurarihyon clan, a family of powerful yokai, Rokujin learns from his grandfather, the current Nurarihyon, about the clan's history and his own role in it. The stories delve into various battles between the Nurarihyon clan and their enemies, including the Tsuchigumo clan, showcasing Rokujin's growth and development as a yokai.