The post-apocalyptic Japanese landscape is characterized by an arid environment and widespread rust. This condition is thought to be caused by mushroom spores. Bisco Akaboshi, a skilled archer, is wanted for his ability to make mushrooms grow from his arrows, but he actually uses this power to spread fungi and restore the land. He travels with Akutagawa and Milo Nekoyanagi to find the Sabikui, a legendary mushroom that can consume rust.